January 23, 2008

Transgenic animal production and animal biotechnology

Posted on 1/23/2008 by Thavrak

Considerable progress has been made in methods for production of transgenic livestock; beginning with pronuclear microinjection over 20 years ago. New methods, including the use of viral vectors, sperm-mediated gene transfer and somatic cell cloning, have overcome many of the limitations of pronuclear microinjection. It is now possible to not only readily make simple insertional genetic modifications, but also to accomplish, more complex, homozygous gene targeting and artificial chromosome transfer in livestock.
Source: Theriogenology, Vol 67, 2007, Pages 127-133

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